Crocin Mitigates Glutamate Excitotoxicity and Tau Hyperphosphorylation by Modulating EAAT2 and Akt/Tau Pathway in a Scopolamine-induced Rat Model of Alzheimer's Disease.

Neurochem Res · 2026 · PMC12963091 · PMID 41784832

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highly significantP ≤ 0.001actually significant

Morphometric Assessments Thickness of the Stratum Pyramidale (SP) Morphometric analysis of hematoxylin and eosin (H&E)-stained hippocampal sections revealed a highly significant reduction (F (6, 14) = 16.72, P ≤ 0.001) in the thickness of the stratum pyramidale (SP) within the CA1 region in the Sc-treated group compared to both the control and Cr-treated groups.

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