Barely Significant
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Cancer risks and trends between 1997 and 2018, and effects of restored immunity in people living with HIV: Results from the ANRS CO4 French hospital database on HIV.

Int J Cancer · 2026 · PMC12963702 · PMID 41263386

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a decreasing trendno p-value reported
Finally, for breast cancer in women, there was a decreasing trend in standardized IR, but no significant change in SIRs overtime, close to 1.

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an increasing trendno p-value reported
There was an increasing trend in standardized IR for colorectal cancer in both men and women, but the SIR in both sexes did not change overtime and was significantly higher than in the general population at 3.0 (95% CI, 2.8–3.3) in men and 3.9 (95% CI, 3.4–4.4) in women in the last period.

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