CCR8 orchestrates an immunosuppressive niche in the liver to promote Echinococcus multilocularis infection.

Consistent with these pathological changes, the levels of serological markers of liver injury – alanine aminotransferase (ALT) and aspartate aminotransferase (AST) – generally showed an increasing trend during the infection course, with statistically significant differences observed at multiple time points ( Fig 1C ).

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