Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom.

PLoS One · 2026 · PMC12965681 · PMID 41790840

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Insulin resistance is both a major pathological and clinical feature of polycystic ovary syndrome [5–7], making the development of an animal model highly significant for advancing research into this condition [8].” 2.

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