Middle Meatal Spacers for Synechiae Prevention Following Endoscopic Sinus Surgery: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Laryngoscope Investig Otolaryngol · 2026 · PMC12967615 · PMID 41804365

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a nonsignificant trendno p-value reported

Discussion This updated systematic review and meta‐analysis demonstrates a significant reduction in postoperative MM synechiae with spacer use compared with no spacer, representing an important evolution of the evidence since the 2012 review by Lee and Grewal, which identified only a nonsignificant trend favoring spacers.

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