A Multi-Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice.

Aging Cell · 2026 · PMC12968584 · PMID 41797510

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a decreasing trendno p-value reported

While Indole‐3‐propionic acid (IPA) showed a decreasing trend (non‐significant), pro‐oxidative and signaling metabolites, including Indole‐3‐acetic acid (IAA) and Indolelactic acid, were significantly accumulated across the gut‐brain axis.

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