Estimating the historical minimum false-positive risk of statistically significant reported outcomes in anaesthesia and pain medicine.

Anaesthesia · 2026 · PMC12973333 · PMID 41657241

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barely statistically significantno p-value reported

As shown in Figure 1b , this is of particular importance in the case of barely statistically significant outcomes: for those 32% of the outcomes, the median minimum risk of falsely declaring the existence of a treatment effect is 23% and can reach up to 32%.

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