Barely Significant
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hsa_circ_0006168 drives microglial activation in TNC via miR-99b-5p/KDM6B axis to promote central sensitization in migraine.

J Headache Pain · 2026 · PMC12977434 · PMID 41654728

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a decreasing trendno p-value reported
Conversely, compared with the mimic NC group, the miR-99b-5p overexpression group presented a decreasing trend in KDM6B expression, although the difference was not statistically significant (Fig. 8 F).

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