Exposure to high-altitude hypobaric hypoxic environment induces low-frequency hearing loss in C57BL/6J mice: Mediated by slowing down the postsynaptic electrical signal transmission speed in the cochlear-inferior colliculus auditory signaling pathway.

Among them, the degree of latency prolongation showed a decreasing trend in the 10-day group and 20-day group ( Fig 2A ).

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Results of wave II and wave III amplitudes under 8000 Hz short pure tone stimulation: In the analysis of Auditory Brainstem Response (ABR) wave amplitudes: the amplitude of Wave II showed differentiated changes: the 5-day group and 15-day group exhibited an increasing trend, while the 3-day group, 7-day group, 10-day group, 20-day group, 25-day group, and 35-day group showed a decreasing trend.

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