Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1<sup>+</sup>TAMs in immunotherapy response in non-small cell lung cancer.

Front Immunol · 2026 · PMC12979556 · PMID 41836417

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highly significantno p-value reported

The results indicated that in every sample, the tendency for co-localization between the two far exceeded random distribution, and both the Aggregation Index and Cohen’s d were highly significant( Supplementary Figure 6 ).

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Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1&lt;sup&gt;+&lt;/sup&gt;TAMs in immunotherapy response in non-small cell lung cancer.

The sentences

Integrative multi-omics and machine learning reveals the spatial niche distribution and role of CYP27A1<sup>+</sup>TAMs in immunotherapy response in non-small cell lung cancer.