Barely Significant
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Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial.

JAMA Netw Open · 2026 · PMC12980234 · PMID 41811317

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highly significantno p-value reported
A key finding from the linear mixed-effects model was a highly significant group-by-time interaction effect specifically for NE, indicating that sivelestat dynamically altered the temporal trajectory of its primary pharmacologic target.

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