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Synthesis of 2‑Quinolones via Thiolate-Mediated Cyclization of (<i>E</i>)‑2-Aminocinnamic Acid Derivatives.

ACS Omega · 2026 · PMC12980447 · PMID 41835498

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highly significantno p-value reported
Consequently, the development of mild, operationally simple, and transition-metal-free methods for accessing 2-quinolones directly from 2-aminocinnamic acids remains a highly significant and desirable objective.

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