The Role of Thyroid Hormone Signaling in the Development and Pathophysiology of Hearing: From Molecular Mechanisms to Clinical Applications.

Int J Mol Sci · 2026 · PMC12984108 · PMID 41828421

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a decreasing trendno p-value reported

DIO2 mRNA expression also increased from birth to a peak at P7 and showed a decreasing trend after P8 [ 21 , 22 ].

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an increasing trendno p-value reported

Publicly available RNA sequencing and microarray datasets also showed an increasing trend in the expression levels of TH transporters (Slc16a2, Slco1c1, Slc10a1, Slco2b1, Slc7a5) in the developmental cochlea ( Supplementary Figure S1B–D ).

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