Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ<sub>1</sub>R Agonists/HDAC Inhibitor Dual-Acting Compounds.

A dose of 100 μg of this compound was administered intraplantarly (i.pl.) to loperamide‐treated animals, producing a highly significant increase in the antinociceptive effect (Figure S9A).

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