Association of Vitamin D and Weight Status With Neurodevelopmental Outcomes in a Large Pediatric Population: Cross-Sectional Study.

Among girls, while the original P values indicated significant associations before FDR corrections across all weight categories (all P <.05), these associations remained statistically robust primarily in the normal-weight group (OR 1.61, 95% CI 1.30-2.00; P <.001; q <.006) and showed a marginal significance in the underweight and overweight/obesity groups (all q =.06).

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For results where the original P value was <.05 but the q value fell between .05 and .10, the associations were interpreted as “marginally significant” or “suggestive trends” rather than definitive findings, ensuring a more conservative and prudent interpretation of our results.

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The attenuation from significance ( P <.05) to a marginal trend ( q =.06) after FDR correction likely reflects the reduced statistical power within these smaller samples of weight-extreme strata, rather than a true absence of biological effects.

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