A Retrospective Study of Hepatic Arterial Infusion Chemotherapy Combined with Tyrosine Kinase Inhibitors and PD-1 Inhibitors in Hepatocellular Carcinoma Patients with Main Portal Vein Tumor Thrombus (VP4).

J Hepatocell Carcinoma · 2026 · PMC12988468 · PMID 41836602

Europe PMC DOI

hedged sentence

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

borderline significantp = 0.067so close (0.05 < p ≤ 0.1)

Tumor number ≥4 demonstrated a borderline significant association with worse PFS (HR: 1.946, 95% CI: 0.954–3.970, p = 0.067) and was therefore included in the multivariate model.

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