Circumferential Negative Pressure Lymphedema Therapy: A Novel Rapid Perioperative Decongestion Strategy for Advanced Stage III-IV Lymphedema.

Cureus · 2026 · PMC12989139 · PMID 41841070

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highly significantno p-value reported

Results: CNPLT produced highly significant limb circumference reductions at all sites: mid-foot (5.7 ± 1.2 cm), lateral malleolus (17.5 ± 2.8 cm), 10 cm above (17.4 ± 3.1 cm), and 20 cm above (14.0 ± 2.8 cm) (all p = 0.001).

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