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Male sex assignment in severely virilized 46,XX children with congenital adrenal hyperplasia.

Front Endocrinol (Lausanne) · 2026 · PMC12989325 · PMID 41847449

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an increasing trendno p-value reported
According to the North American DSD Clinician Survey, based on pediatric endocrinologists and urologists’ experiences over the past two decades, there is an increasing trend toward recommending a gender “other than girl” for 46,XX CAH patients with severe virilization and to perform genital surgery later in life ( 11 ).

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