Distinct metabolic and genetic alterations in tumors from early-onset versus late-onset colorectal cancer.

Free Radic Biol Med · 2025 · PMC12990094 · PMID 40865779

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Cluster of differentiation 40 (CD40) and carbonic anhydrase (CA9) were highly significant and predicted to be activated in both tumor groups, whereas O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and carnitine palmitoyltransferase 1B (CPT1B) were inhibited.

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