Cost-effectiveness of routine influenza vaccination program for individuals aged 65 years and older in Japan: Substituting standard-dose inactivated vaccine with high-dose inactivated vaccine.

IJID Reg · 2026 · PMC12992081 · PMID 41852922

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a slightly increasing trendno p-value reported

Also, we adopt same rVE to all age, which is in contrast to a previous study that evaluated the effect of age on rVE of HD vs SD influenza vaccine (from 2012 to 2018 season) reported that there had been a slightly increasing trend in rVE with age in all seasons, especially was consistently more effective than SD for adults aged ≥85 years [ 34 ].

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