The midline increase with rst RNAi was lower than with hbs , but still highly significant ( Figures 1 I–1L). kirre and sns , which have been found to interact with hbs or rst in other contexts, were not among the “ in silico ” candidates, but when tested in vivo , did not appear to cause significant midline phenotypes ( Figure S1 L).
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Hbs and Rst adhesion molecules provide a regional code that regulates cell elimination during epithelial remodeling.
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