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Comparison of retention of resin-based filled and unfilled pit and fissure sealants using different isolation techniques.

Sci Rep · 2026 · PMC12992619 · PMID 41691032

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an increasing trendno p-value reported
Importantly, analyses of 2021 global burden data have demonstrated an increasing trend in caries prevalence over the past decade, particularly among children, underscoring that dental caries remains a persistent public health challenge despite advances in preventive strategies 1 – 3 .

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