Therefore widespread use of effective vaccines may induce a major impact in preventing the disease, especially when they are used during a long period of time as a part of the NIP, as occurred in Cuba, where a decreasing trend of BM has been documented after vaccination against meningococcus serogroup B and C, and more recently, Hib [ 4 , 9 , 10 , 12 ].
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Bacterial meningitis in children and adolescents: an observational study based on the national surveillance system.
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