Gut microbiota diversity is altered in a sex-dependent manner in Shank3B heterozygote mice.

Front Microbiomes · 2025 · PMC12993676 · PMID 41852439

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hedged sentences

0.0032

closest p · 0.1× alpha

0.0580

boldest claim

The sentences

highly significantp = 0.0032actually significant

There is a highly significant interaction between genotype (treatment) and sex (p = 0.0032).

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marginally significantp = 0.058so close (0.05 < p ≤ 0.1)

The Beta diversity analysis (PERMANOVA, Figure 3 ) using Bray-Curtis dissimilarity shows a marginally significant effect of genotype (R2 = 0.40792, p = 0.058), no significant effect of sex (R2 = 0.00292, p = 0.941) and a significant interaction between genotype (treatment) and sex (R2 = 0.64994, p = 0.003).

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