Evaluation of Resistance Dynamics in Pseudomonas aeruginosa Isolated From ICUs of a Tertiary-Level Hospital in Eastern India: A Five-Year Study.

Cureus · 2026 · PMC12993792 · PMID 41853438

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

After applying the Holm-Bonferroni correction to all nine trends, a highly significant decreasing trend in AMR from 2021 to 2025 was observed for piperacillin/tazobactam (adjusted p < 0.001) and meropenem (adjusted p < 0.001).

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an increasing trendno p-value reported

aeruginosa isolates continue to show an increasing trend in our setting.

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a decreasing trendno p-value reported

This study also demonstrates a decreasing trend in resistance to piperacillin/tazobactam, imipenem, cefepime, meropenem, ciprofloxacin, aztreonam, levofloxacin, and ceftazidime over five years, potentially reflecting judicious antibiotic use.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.