Trend and burden of lower-limb amputations due to diabetes: time series analysis, Amazonas, 2012-2021.

Epidemiol Serv Saude · 2026 · PMC12995277 · PMID 41849464

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an increasing trendno p-value reported

Discussion Between 2012 and 2021, an increasing trend in lower-limb amputation procedure rates was observed, with a high burden of diabetes-related lower-limb amputations, particularly among men and individuals aged 45–64 years during the 2017–2021 period.

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