Stress fiber traction force reshapes chromatin accessibility and YAP binding to direct diverse transcriptional programs in mesenchymal stem cells.

Synergistic regulation of signaling pathways by altered chromatin accessibility and YAP targeting To identify upstream regulatory pathways that may coordinately control multiple functional modules under reduced cytoskeletal force, we systematically selected KEGG pathways that were highly significant in both ATAC-seq and YAP CUT&Tag datasets, excluding disease-associated pathways ( Fig. 5 a).

also in 132,142 other papers