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Temperature dependent behavior of hydrogen-bonded liquids: bridging experiments with molecular dynamics and DFT.

Sci Rep · 2026 · PMC12996422 · PMID 41692911

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a notable trendno p-value reported
A notable trend emerges with increasing alcohol chain length: the binding energy difference (E 2 -E 1 ) becomes progressively less negative, suggesting that steric hindrance from longer alkyl substituents reduces the relative advantage of ROH···HP interactions.

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