4 F), a marginally significant increase in the number of entries in the arena's center was detected by Hprt ALPL, CKIICre mice compared to WT mice ( Supplementary Fig. 3D ).
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Neuronal alkaline phosphatase promotes the spread of Tau-induced pathology, and its blockade prevents neurodegeneration and memory loss.
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Marginal significance was considered at # P ≦ 0.08.