Impact of Liraglutide on Insulin Clearance in Patients with Type 2 Diabetes Mellitus: Evidence from a Randomized Controlled Trial.

Diabetes Metab J · 2026 · PMC12996959 · PMID 41813267

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a nonsignificant trendno p-value reported

In a crossover trial in which 30 patients with T2DM and coronary artery disease received 12-week courses of liraglutide and placebo in random sequence, insulin clearance did not differ between the interventions, though there was a nonsignificant trend towards higher clearance with liraglutide in completer analyses consisting of only 73% of 41 randomized participants [ 9 ].

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