Barely Significant
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Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021.

Korean J Intern Med · 2026 · PMC12999252 · PMID 41850226

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a decreasing trendno p-value reported
In contrast, the total number of DALYs showed a decreasing trend, declining from 5,745.00 thousand (95% UI, 4,914.84 to 6,594.17) in 1990 to 4,846.98 thousand (3,914.84 to 5,494.17) in 2021 ( Supplementary Fig. 4 and Supplementary Table 7 ).

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