Dissecting gene regulatory networks governing human cortical cell fate.

Nature · 2026 · PMC12999477 · PMID 41565813

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an overall trendno p-value reported

Repression of PHF21A —a member of the BRAF/HDAC complex implicated in synapse formation 84 —led to an overall trend towards EN over IN differentiation (Fig. 3a and Extended Data Fig. 3e,f ), matching the effects of targeting other ASD causal genes ARX and CTCF 85 , 86 .

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