No-touch versus conventional radiofrequency ablation for treating solitary recurrent hepatocellular carcinoma ≤ 3 cm: a retrospective cohort study.

J Cancer Res Clin Oncol · 2026 · PMC13000070 · PMID 41848917

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a decreasing trendno p-value reported

While postoperative AFP levels showed a decreasing trend compared to preoperative levels in the NT-RFA group, AFP levels did not undergo remarkable changes in the C-RFA group, and 36.36% (8/22) of AFP-positive patients in the NT-RFA group and 16.42% (11/67) in the C-RFA group turned AFP-negative (≤ 20 ng/ml), with a significant difference between the two groups ( P = 0.048).

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