Marked clinical and haemodynamic improvement with sotatercept in severe refractory pulmonary arterial hypertension associated with corrected complex congenital heart disease.

Respir Med Case Rep · 2026 · PMC13000717 · PMID 41868707

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highly significantno p-value reported

PAH-CHD often involves unique mechanisms such as chronic RV pressure overload and fixed pulmonary vascular disease, making the degree of "reversibility" observed here highly significant.

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