Glymphatic dysfunction as a predictor of response to lacosamide add-on therapy in drug-resistant focal epilepsy.

Front Neurol · 2026 · PMC13002404 · PMID 41868487

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0.0960

closest p · 1.9× alpha

0.0960

boldest claim

The sentences

a trend toward significancep = 0.096so close (0.05 < p ≤ 0.1)

Age of seizure onset was not statistically significant in the multivariable model ( p = 0.168) The DTI-ALPS index showed a trend toward significance ( p = 0.096) but did not remain statistically significant after adjusting for clinical covariates. 4.

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