Two-way ANOVA revealed a highly significant main effect of treatment, with post-hoc analysis confirming that the combination therapy elicited a significantly stronger apoptotic response than either monotherapy alone across all organoid lines, providing robust quantitative validation of the synergistic apoptosis induction ( Figure 4B ).
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Saikosaponin D Induced Apoptosis and Anti-Tumor Effect Enhancing Chemotherapy Sensitivity of Gemcitabine in Patient-Derived Cholangiocarcinoma Organoids.
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