We further confirmed by western blot that the level of M1 activation key factor phosphorylation of STAT1 (p-STAT1) significantly increased in the ZIF-8@XOR group, while M2 activation factor phosphorylation of STAT6 (p-STAT6) exhibited a decreasing trend (Fig. 4 C).
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XOR-mediated tumor-selective nanomaterial therapy: achieving tumor and immune cell dual regulation through intracellular ROS generation.
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