In addition, "cellular stress response" (GO:0070887) and "mitochondrial function regulation" (GO:0034599) were also highly significant, further supporting the key roles of OS and mitochondrial dysfunction in AD (Suppl Figure 2.1 displays a combined bubble plot illustrating the enrichment results for all three steps ).
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Integrative SMR prioritizes oxidative stress-related regulatory genes for Alzheimer's disease with brain-tissue validation.
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