Barely Significant
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Associations of white matter hyperintensity regression and progression with cognitive and structural brain changes: a population-based cohort study.

Alzheimers Res Ther · 2026 · PMC13014974 · PMID 41699639

Europe PMCDOI
1
hedged sentence
0.0620
closest p · 1.2× alpha
0.0620
boldest claim

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marginally significantp = 0.062so close (0.05 < p ≤ 0.1)
Specifically: (1) after excluding missing covariates (Table S2): the association of “total WMH regression” with processing speed decline became marginally significant ( p = 0.062), as did “DWMH progression” with HV loss ( p = 0.061).

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