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A tonic electrocutaneous stimulation paradigm for graded sensory C-fiber engagement in healthy subjects.

Front Pain Res (Lausanne) · 2026 · PMC13017951 · PMID 41908031

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an increasing trendno p-value reported
Although the main effect of Time was not significant, high-intensity stimulation exhibited an increasing trend over time, reflecting a tendency toward temporal summation effects that was not observed in lower intensities or in the Aβ-fiber control setting.

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