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Ginkgolic acid targets HSPA8 to trigger ferroptosis in hepatocellular carcinoma <i>via</i> chaperone-mediated autophagy-dependent GPX4 degradation.

Pharm Biol · 2026 · PMC13021020 · PMID 41877645

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a decreasing trendno p-value reported
Consistent with these results, GAC treatment markedly decreased GPX4 protein levels, and SLC7A11 protein levels also showed a decreasing trend ( Figure 2(A–D) ).

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