Barely Significant
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Effects of Guanidinoacetic Acid and Metabolizable Energy Levels on Performance and Nutrient Metabolism in Broilers.

Animals (Basel) · 2026 · PMC13023316 · PMID 41897912

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failed to reach significanceno p-value reported
In our trial, GAA increased AME/AMEn only in the positive-energy control (PC) ( Table 4 ), but failed to reach significance in the −50 and −100 kcal/kg diets for several context-dependent reasons: (i) lipid environment—lowering soybean oil to achieve ME reduction compromises emulsification and passage rate, conditions under which enterocyte benefits from creatine-supported ATP buffering are blunted, while energy responses to diet energy are well known to depend on lipid level/quality and feed form [ 23 , 34 ]; (ii) ME vs.

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