Skin-Based α-Synuclein Deposits Detection Across the Prodromal Continuum of Synucleinopathies: Updated Evidence and Perspectives.

Biomolecules · 2026 · PMC13024106 · PMID 41897312

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

PAF is a highly significant non-motor prodromal feature of synucleinopathy, with approximately 33–35% of patients phenoconverting to more widespread neurodegenerative synucleinopathies over time, most commonly to PD, DLB, or MSA [ 56 , 57 , 58 ].

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.