Targeted intracellular oral RNA delivery through tea polyphenol nanovesicle to outer membrane vesicle transfer for colitis treatment.

Sci Adv · 2026 · PMC13025053 · PMID 41894502

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highly significantP < 0.001actually significant

Assessment of DAI revealed that treatment with HVs@HA-BR-KDEL resulted in a highly significant reduction ( P < 0.001 versus model; Fig. 6C ), whereas siRNA-OMVs induced a moderate but significant alleviation of symptoms ( P < 0.05 versus model; fig.

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