Loss of PIK3CA Allows <i>In Vitro</i> Growth but Not <i>In Vivo</i> Progression of KRAS Mutant Lung Adenocarcinoma in a Syngeneic Orthotopic Implantation Model.

When all DEGs were included in this analysis, the most changed pathways in either KPA or KPS in comparison to KP were identical (data available upon request), so we stringently filtered the gene list to prioritize DEGs with a large, highly significant log 2 -fold change compared to KP cells to ensure we only included robust and specifically different genes in GSEA.

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