Notably, olaparib treatment of hMOB2-depleted cells produced a further and highly significant increase in γH2AX foci compared with either control, hMOB2 depletion or olaparib treatment alone ( Figure 2 A,B).
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MOB2 Loss Sensitizes Lung Cancer Cells to PARP Inhibition Through p53-Dependent DNA Damage Signaling.
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