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Metabolomic Study of 7-Ethyl-9-(<i>N</i>-methyl)aminomethyl-10-hydroxycamptothecin Derivative (NMe)-The Chemotherapeutic Drug Candidate Versus Irinotecan (IR) on a Mouse Model.

Metabolites · 2026 · PMC13027767 · PMID 41893323

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a decreasing trendno p-value reported
In contrast, at the corresponding timepoints in the NMe groups, higher levels of SN-38 were observed in females and comparable levels in males, with a decreasing trend over time and only trace amounts of NMe detected.

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