Regional patch-based MRI brain age modeling with an interpretable cognitive reserve proxy.

Pattern Recognit Lett · 2026 · PMC13029012 · PMID 41908685

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp = 8.14 × 10 − 24actually significant

For example, when distinguishing individuals with MCI from those with CN, CR-Proxy showed a highly significant difference ( p = 8.14 × 10 − 24 , Cohen’s d = 0.68 ), compared to Brain-PAD ( p = 6.93 × 10 − 4 , d = − 0.25 ).

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