Previous prospective surveillance studies have also demonstrated a decreasing trend in adverse event incidence across IPV doses, with the first dose exhibiting the highest rate and subsequent doses showing lower rates, a pattern attributed to increased tolerability following initial exposure [ 33 ].
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Safety of Sabin-Strain Inactivated Poliovirus Vaccine Administered Alone or Concomitantly with Other Vaccines: A Population-Based Post-Marketing Surveillance Study.
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