Joinpoint regression analysis supported an overall increasing trend in the incidence rate (AAPC 2012–2025 = 3.89%) and a decreasing trend in mortality (AAPC 2012–2025 = −12.10%) ( Table S1 ).
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Spatiotemporal and Demographic Patterns of West Nile Neuroinvasive Disease in Vojvodina, Serbia, 2012-2025.
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The analysis identified two incidence-rate trend segments, with a change in direction in 2020 from a decreasing trend (APC 2012–2020 = −28.72%) to an increasing trend (APC 2020–2025 = 89.82%) ( Figure S1A ).